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Home > Products > Anti-Cancer Ingredient > cancer treatment Topotecan Hcl

cancer treatment Topotecan Hcl

Basic Info

Model No.: S.Y-A

Product Description

Description of  Topotecan HCL 1.English name:Topotecan
2.Molecular Formula:C23H23N3O5
3.Molecular Weight:421.4458
4.CAS Registry Number:123948-87-8
7.Boiling point:782.9°C at 760 mmHg
8.Refractive index:1.733 Flash point:427.3°C
9.Vapour Pressur:8.13E-26mmHg at 25°C
  Fuction of  Topotecan HCL 1 Topotecan Hydrochloride (Topotecan HCl) is a semi-synthetic derivative of camptothecin. Camptothecin is a natural product extracted from the bark of the tree Camptotheca acuminata. Topoisomerase-I is a nuclear enzyme that relieves torsional strain in DNA by opening single strand breaks. Once topoisomerase-I creates a single strand break, the DNA can rotate in front of the advancing replication fork. Topotecan intercalates between DNA bases. This intercalation disrupts the DNA deplication machinery when it reaches a site where topotecan is intercalated.

2 Topotecan is an antineoplastic agent used to treat small cell lung cancer, and certain cancers of the ovary.

3 Topotecan is also used to treat relapse of small cell lung cancer that initially responded to other drugs. Increases in survival times have been observed in patients treated with topotecan compared to control populations treated with paclitaxel.

  packing&storage  package:25kg/drum,double plastic-bag inside,aluminum foil bag or fiber drum outside. storage:stored in a clean,cool, dry area;keep away frommoisture and stong,direct light/heat. shelf life: two years when properly stored about us                         HENAN SENYUAN BIOLOGICAL TECHNOLOGYCo., an effectivecomponent in natural plants pharmaceutical intermediates and the development, production, sales of high-tech enterprises. Is dedicated to promoting traditional Chinese herbs modernization process, widely used in Chinese Medicine, chemicals, food, health products industries, providing high-quality products and improve the technology and after-sales service.  our services 1. Any inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. OEM/ODM Available. 5. Reasonable & competitive price, fast lead time. 6. Sample is available for your evaluation & Formulation development. 7. Faster delivery: Sample order in stock and 3-7 days for bulk production. 8. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder. 9. After-Sale Service: 1)International Authorized Third-Party Test For The Products You Demand. 2)60 Days Warranty of quality of goods. FAQ Q1: Can i get some samples? A: Yes, we can supply the free sample, but the shipping cost be paid by our customers. Q2: How to start orders or make payments? A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Paypal or Escrow(Alibaba). Q3: How to confirm the Product Quality before placing orders? A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests. Q4:What’s your MOQ? A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid. Q5: How about delivery leadtime? A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included) Q6:Is there a discount? A:Different quantity has different discount. Q7: How do you treat quality complaint? A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss. Q8: How to contact us ? A:You can chat with us by Trademanager,MSN&Skype Online. You can choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.          

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Product Categories : Anti-Cancer Ingredient